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Pro-fission shift in dynamic regulators have also been shown to persist months following P7 SEV including pDRP1(S616) and MFF, and decreases in pro-fusion regulators MFN2 and OPA1, coherent with the morphological findings (67)

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A study in the Journal of Drugs in Dermatology found that the use of copper peptide complexes significantly improved the appearance of fine lines and wrinkles over a 12-week period