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A 100mg vial can last months at lower doses — though the 28-day limit applies once reconstituted with BAC water

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Complementing this approach, researchers have also designed enzyme-responsive self-assembled multivalent apelin ligands (SAMPs), which achieve targeted accumulation at the myocardial infarction site by responding to locally upregulated matrix metalloproteinases, thereby prolonging retention time and enhancing receptor binding affinity (81)