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Introduction Oxidative stress is thought to contribute to the development of a wide range of diseases including neurodegenerative (Alzheimer, Parkinson, Amyotrophic Lateral Sclerosis…), diabetes, cancer, rheumatoid arthritis, cardiovascular and liver diseases several of them are related with low levels of IGFs such as degenerative and aging disorders [1-8]

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Among these, the Mediterranean diet is particularly promising due to its high content of selenium, omega-3 fatty acids, iodine, and antioxidants, all of which may help modulate immune responses and oxidative stress implicated in Hashimoto’s disease [50]