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16 Most APAP-sulfates are excreted into bile by multidrug resistance–associated protein 2 (MRP2), and a few are excreted into bile by human breast cancer resistance protein 1 (BCRP1)

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Other models in neurons have shown that BHB improves the efficiency of mitochondrial respiration by increasing the ratio of oxidized-to-reduced nicotinamide adenine dinucleotide (NAD + /NADH), thereby leading to a decrease in reactive oxygen species and the blunting of cell death induced by glutamate excitotoxicity (102, 103)