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In practice, we routinely see patients lose 20% or more of their starting weight using semaglutide

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Primary antibodies used for detecting shelterin subunits were custom rabbit anti-TRF1 (1:5,000, Thermo Scientific), mouse anti-TRF2 antibody (1:10,000, Abcam ab13579) and mouse anti-TIN2 antibody (1:10,000, Novus Biologicals 59B388.1)