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Although its precise mechanisms remain partially understood, BPC 157 has shown substantial protective effects across various tissues, including the skin [17,18], gastrointestinal tract [19,20,21,22], tendons [23,24], ligaments [25], muscles [26,27], bones [28], myocardium [29], and blood vessels [30,31]

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First-line serplulimab or placebo plus chemotherapy in PD-L1-positive esophageal squamous cell carcinoma: a randomized, double-blind phase 3 trial