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Common tirzepatide reconstitution: 5mg vial + 1mL BAC water = 5mg/mL → For a 2.5mg dose, draw 50 units 10mg vial + 2mL BAC water = 5mg/mL → For a 2.5mg dose, draw 50 units 10mg vial + 1mL BAC water = 10mg/mL → For a 5mg dose, draw 50 units 30mg vial + 3mL BAC water = 10mg/mL → For a 5mg dose, draw 50 units Tirzepatide is injected once weekly, subcutaneously

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There was also no significant difference between SHAM and IRB groups in terms of Hif-1α expression ( p = 0.059)

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