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Predrag Sikiric, [email protected] This article was submitted to Translational Pharmacology, a section of the journal Frontiers in Pharmacology Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

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This activation of NAD+ then supports SIRT1 pathways, which are crucial for mitochondrial function, fat oxidation, and overall metabolic flexibility